I use an air powered Brad nailer for frames. 18 ga. 1" (I think) for frame assy (2 from the top, 4 from the sides, & 2 from the bottom), and 1/2" brads (3x) for the flipped wedge bar - I'm foundationless.
100 frames takes me around 2 hrs. I assemble 10 or 12 fames upside down, lay my arm across them to hold, and go down the line nailing the bottom 2 nail. Then flip them onto the side for 4 more, then upright for the last 2 nails. When all are done, I pull up a chair and start flipping and nailing the wedge bars. It goes quick.
This has worked for me for the last 3 yrs. I don't glue them anymore - the bees do that. Haven't had any problems. Extracts fine if the comb is connected on all 4 sides.