Thanks, Ace, MB for the comments, so noted.
MB{You are selecting for virulent mites whenever you treat.}
This is correct if one is referring to a miticide that has a prominent mode of action (such as inhibition of cell wall synthesis, penicillin) as most antibiotics vs bacteria, very true. However when I do treat I treat with oxalic acid (a natural component of Honey) with has multi modes of action which poses the question in resistance even possible.
oxalic acid has so many modes of action to a Varroa mite, compare the acid to fire: pertaining to modes of action only. Can an organism resist or acquire resistance to fire with so many modes of action. Certainly fire has more modes of action than oxalic acid, I am exaggerating to make a point.
I cannot state resistance is impossible, I worked with antibiotic resistant organisms for decades in a P4 laboratory in which there about 3-4 such labs in the US. P4 laboratorys are the highest secured labs on the planet. One can?t not even walk into these laboratories without passing through multiple armed Federal Guards. Doors are automatically controlled via a Body sensor and passage is tracked.
My boss would present me a particular bacterium, note fatalities, P3, then advise me to discover the genesis of resistance. How did the organism acquired resistance to multi antibiotics.
So even with multi modes of action, for oxalic acid I just cannot say ?resistance is impossible? but I consider resistance unlikely, given so many modes of action with oxalic acid.
Blessings