An acquaintance, now a friend, a first year beekeeper had me come over to inspect his hive with him last Oct. 2 minutes into it I thought it was doomed, DWV in 50% of the bees at least. Queen looked ok, I marked her for him. We did a sugar shake, full of mites. I explained the severity of the situation to him. With nothing to lose i had him do the 3 days 7 times with double the dose. Sugar shake in early Dec, better but. Treated again. Jan. Still DWV but better, fewer bees also. February, wax moths, pulled and froze some frames and tore out some worm damage on frames with brood in them. Had him order some Xentari. He mixed at 1 tsp in a gal, shook the bees off and sprayed the comb, brood and all. We inspected this past Tuesday and one would not think it is the same hive, repaired comb, little to no DWV, lots of capped brood and bringing in pollen and nectar. He also has the same marked queen which should have burnt antenna and all kinda bad things wrong with her from all that OA I'm told.
Now I have to gently explain to him that the honey he so proudly gave me from those frozen frames using the crush and strain is mostly sugar water.