Wow, some good questions, Phil. As usual I might add.
A virus is not a living organism, a particle, so killing is not possible. The DNA or RNA of the virion (singular) can be destroyed by a number of means, described below.... But destroying every single particle is daunting as demonstrated by the best attempts to control covid. With the most aseptic means possible, medical personal became infected.
To sterilize a hive body and parts thereof, gloves, tools, etc, included is just not feasible. One would have to fumigate with formalin, which is a deadly gas or heat combined with pressure or soak in ether, or pure ammonia, again, very deadly.