I opened up one of my over winter hives and found the queen had laid a full medium frame of eggs on the first frame, frame #1. A week latter I went in again and all the eggs were gone expect for a small area in the middle of the frame and they had capped that. Today I pulled frame #1 and everything was gone and they were filling it with nectar. What happen to my eggs and brood in less than 2 weeks?
Q1: How old is this queen? If an old queen, her eggs may not be viable. The bees remove and eat dud eggs. If old or poorly mated she may have gone drone layer. Too early in the season the bees do not want drones. The bees may remove and eat drone eggs until there are enough amounts of resources coming in.
Q2: Look for evidence of brood diseases or pms. Is there something killing the brood causing them to remove it?
Q3: Mites; what is the mite load in the hive? What controls have you implemented?
Q4: How many bees are in the hive? Are there enough bees to look after the brood? All that the queen does is lay the eggs. The bees do everything else. If the queen outlays the capacity of the bees, the bees will remove and eat the excess eggs and larvae that they cannot look after.
Q5: What is the resources level in the hive? Do they have plenty of pollen in stores or coming in from foraging? When food is shorted, the bees cut back on the brood - eating the eggs and the larvae.
Hope that helps!