There is no issue with drone comb being used for honey, as Michael said, but if the bees are on foundation and are restricted in the amount of drones they are allowed to raise, any space where they can draw freely they will probably put drone brood in, not honey. If you are foundationless and let the bees maintain some drone brood, this is less of a problem, since they aren't gunning to make drone brood at the first opportunity.